DMAA, also known as 1,3-dimethylamylamine (1,3-DMAA) and Methylhexanamine, is an indirect sympathomimetic drug that constricts blood vessels and thus has effects on the heart, lungs, and reproductive organs. It also causes bronchodilation, inhibits peristalsis in the intestines, and has diuretic effects.[4]:95 Most studies have been done on pharmacological effects when the drug is inhaled; our understanding of what methylhexanamine does when taken orally are mostly based on extrapolating from the activities of similar compounds.[4]:97 A 2013 review concluded that: “Pharmacological effects after oral intake can be expected on the lungs (bronchodilation) and the nasal mucosa following a single oral dose of about 4–15 mg. Pharmacological effects on the heart can be expected following a single oral dose of about 50–75 mg. Pharmacological effects on the blood pressure can be expected after a single oral dose of about 100 mg. Because of the long half-life, there is a risk that repeated doses within 24–36 hours could lead to steadily stronger pharmacological effects (build-up).”

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